{"id":475,"date":"2023-08-13T05:54:08","date_gmt":"2023-08-12T20:54:08","guid":{"rendered":"https:\/\/www.aya199166.com\/?p=475"},"modified":"2025-11-11T03:36:09","modified_gmt":"2025-11-10T18:36:09","slug":"aya199166-com-2023","status":"publish","type":"post","link":"https:\/\/www.aya199166.com\/?p=475","title":{"rendered":"\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u3057\u3088\u3046"},"content":{"rendered":"\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img fetchpriority=\"high\" decoding=\"async\" width=\"366\" height=\"164\" src=\"https:\/\/www.aya199166.com\/wp-content\/uploads\/2024\/06\/g0022-e1759355074401.png\" alt=\"\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u3092\u3057\u3088\u3046\" class=\"wp-image-9859\" style=\"width:570px;height:auto\" srcset=\"https:\/\/www.aya199166.com\/wp-content\/uploads\/2024\/06\/g0022-e1759355074401.png 366w, https:\/\/www.aya199166.com\/wp-content\/uploads\/2024\/06\/g0022-e1759355074401-300x134.png 300w\" sizes=\"(max-width: 366px) 100vw, 366px\" \/><\/figure>\n<\/div>\n\n\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_83 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.aya199166.com\/?p=475\/#%E3%82%AA%E3%83%BC%E3%83%88%E3%83%95%E3%82%A1%E3%82%B8%E3%83%BC%E3%81%97%E3%82%88%E3%81%86\" >\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u3057\u3088\u3046<\/a><ul class='ez-toc-list-level-2' ><li class='ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.aya199166.com\/?p=475\/#%E3%82%AA%E3%83%BC%E3%83%88%E3%83%95%E3%82%A1%E3%82%B8%E3%83%BC%E3%81%97%E3%82%88%E3%81%86-2\" >\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u3057\u3088\u3046<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.aya199166.com\/?p=475\/#%E3%82%AA%E3%83%BC%E3%83%88%E3%83%95%E3%82%A1%E3%82%B8%E3%83%BC%E3%81%97%E3%82%88%E3%81%86-3\" >\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u3057\u3088\u3046<\/a><\/li><\/ul><\/li><\/ul><\/li><\/ul><\/nav><\/div>\n<h1 style=\"text-align: center;\"><span class=\"ez-toc-section\" id=\"%E3%82%AA%E3%83%BC%E3%83%88%E3%83%95%E3%82%A1%E3%82%B8%E3%83%BC%E3%81%97%E3%82%88%E3%81%86\"><\/span><span style=\"color: #000000; background-color: #ffff99; font-size: 20px;\">\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u3057\u3088\u3046<\/span><span class=\"ez-toc-section-end\"><\/span><\/h1>\n<p><span style=\"font-size: 20px; color: #000000;\">\u3055\u3066\u3001\u4eba\u751f100\u5e74\u6642\u4ee3\u306b\u5165\u3063\u3066\u3001\u8ab0\u3082\u304c\u9577\u5bff\u547d\u306b\u306a\u308b\u3088\u3046\u3060\u3051\u3069\u3001\u4eba\u751f\u306e\u534a\u5206\u3092\u75c5\u6c17\u3067\u82e6\u3057\u3093\u3060\u308a\u3001\u75c5\u9662\u751f\u6d3b\u3063\u3066\u306e\u306f\u30b4\u30e1\u30f3\u3060\u3068\u8ab0\u3082\u304c\u601d\u3044\u307e\u3059\u3002\u3060\u304b\u3089\u3053\u305d\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u3057\u3088\u3046\u2026\u306a\u306e\u3067\u3059\u3002<\/span><\/p>\n<p><span style=\"font-size: 20px; color: #000000;\"><strong>\u7a00\u306b\u9577\u5bff\u3067\u5065\u5eb7\u3067\u82e5\u3005\u3057\u3044\u4eba\u306a\u3093\u304b\u3092\u30c6\u30ec\u30d3\u30cb\u30e5\u30fc\u30b9\u3067\u898b\u305f\u308a\u3001TV\u756a\u7d44\u306e\u7279\u96c6\u304c\u3042\u3063\u305f\u308a\u3057\u3066\u3001\u2025\u305d\u306e\u5065\u5eb7\u3055\u306b\u30d3\u30c3\u30af\u30ea\u3067\u3059\u304c\u3001\u6700\u8fd1\u306b\u306a\u308a\u3001\u305d\u306e\u4ed5\u7d44\u307f\u304c\u6b21\u3005\u3068\u89e3\u660e\u3055\u308c\u3066\u3044\u308b\u3088\u3046\u3067\u3059\u3002<\/strong><\/span><\/p>\n<div class=\"box_style box_style_red\">\n<div class=\"box_inner\">\n<div class=\"box_style_title\"><span style=\"color: #ffffff; font-size: 20px;\"><strong><span class=\"box_style_title_inner\">\u75c5\u7406\u30fb\u751f\u7406\u5b66\u304b\u3089\u3002<\/span><\/strong><\/span><\/div>\n<p><span style=\"font-size: 20px; color: #000000;\"><strong>\u9577\u5bff\u3067\u5065\u5eb7\u3063\u3066\u306e\u306f\u5076\u3005\u3001\u751f\u7406\u5b66\u8005\u3055\u3093\u304c\u89e3\u304d\u660e\u304b\u3057\u305f\u4eba\u4f53\u751f\u7406\u5b66\u306e\u4ed5\u7d44\u3068\u89e3\u660e\u3068\u65b9\u6cd5\u306b\u5f53\u3066\u306f\u307e\u308b\u3093\u3060\u3063\u3066\u3002\u3000\u5b9f\u306f\u4eba\u9593\u306b\u306f\u300c\u81ea\u5df1\u4fee\u5fa9\u6a5f\u80fd\u300d\u304c\u5099\u308f\u3063\u3066\u3044\u308b\u3051\u3069\u3001\u8ab0\u3082\u305d\u306e\u6a5f\u80fd\u3092\u77e5\u3089\u305a\u306b\u4eca\u8fc4\u3001\u751f\u304d\u3066\u6765\u305f\u3088\u3046\u3067\u3059\u3002<\/strong><\/span><\/p>\n<p><span style=\"font-size: 20px; color: #000000;\"><strong>\u3044\u308f\u3086\u308b\u75c5\u6c17\uff08\u30a6\u30a4\u30eb\u30b9\u611f\u67d3 \u542b\uff09\u3068\u3044\u3046\u306e\u306f\u30bf\u30f3\u30d1\u30af\u8cea\u7d30\u80de\u306e\u52a3\u5316\u3084\u7570\u5e38\u306b\u3088\u3063\u3066\u5f15\u304d\u8d77\u3053\u3055\u308c\u308b\u75be\u75c5\u3060\u305d\u3046\u3067\u3059\u3002<\/strong><\/span><\/p>\n<\/div>\n<div class=\"box_inner\"><span style=\"font-size: 24px; color: #000000;\"><strong><span style=\"font-size: 20px;\">\u4eba\u9593\u306b\u306f\u7d04\u300137\u5146\u500b\u306e\u7d30\u80de\uff08\u30bf\u30f3\u30d1\u30af\u8cea\u7d30\u80de\uff09\u304c\u6709\u308a\u3001\u305d\u306e\u4e2d\u306b\u306f\u5fc5\u305a\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u3068\u3044\u3046\u3001\u30a8\u30cd\u30eb\u30ae\u30fc\uff08\u71b1\uff09\u3092\u4f5c\u308b\u3082\u306e\u304c\u3042\u308b\u305d\u3046\u3067\u3059\u3002<\/span>\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000<\/strong><\/span><\/div>\n<div class=\"box_inner\"><span style=\"font-size: 24px; color: #000000;\"><strong>\u3060\u304b\u3089\u3053\u305d\u3001\u4eba\u9593\u306e\u8eab\u4f53\u306f\u6696\u304b\u304f\u3001\u6b7b\u3093\u3067\u3057\u307e\u3046\u3068\u51b7\u305f\u304f\u306a\u308b\u306e\u3067\u3059\u3002\u3067\u3059\u304b\u3089\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306f\u5927\u5207\u306a\u5668\u5b98\u3067\u3059\u304c\u3001\u58ca\u308c\u305f\u308a\u2026\u7a81\u7136\u5909\u7570\u3092\u8d77\u3053\u3057\u305f\u5834\u5408\u3001\u4eba\u9593\u306f\u75c5\u6c17\u306b\u306a\u3063\u3066\u3057\u307e\u3063\u305f\u308a\u3001\u305d\u308c\u304c\u539f\u56e0\u3067\u4ea1\u304f\u306a\u3063\u3066\u3057\u307e\u3044\u307e\u3059\u3002<\/strong><\/span><\/div>\n<\/div>\n<div>\n<div class=\"box_style box_style_blue\">\n<div class=\"box_inner\">\n<div class=\"box_style_title\"><span class=\"box_style_title_inner\" style=\"font-size: 20px;\">\u5927\u9685\u6804\u8a89\u6559\u6388\u306e\u7814\u7a76\u3002<\/span><\/div>\n<p><span style=\"font-size: 20px;\"><strong>\u30b9\u30a6\u30a7\u30fc\u30c7\u30f3\u306f\u30012016\u5e74\u306e<span style=\"text-decoration: underline; color: #ff0000;\">\u30ce\u30fc\u30d9\u30eb\u533b\u5b66\u751f\u7406\u5b66\u8cde<\/span>\u3092<span style=\"text-decoration: underline;\"><span style=\"color: #ff0000; text-decoration: underline;\">\u5927\u9685\u826f\u5178<\/span>(\u304a\u304a\u3059\u307f \u3088\u3057\u306e\u308a)<\/span> \u6771\u4eac\u5de5\u696d\u5927\u5b66\u6804\u8a89\u6559\u6388(71)\u306b\u6388\u4e0e\u3059\u308b\u3068\u767a\u8868\u3057\u307e\u3057\u305f\u3002\u3000\u6388\u8cde\u7406\u7531\u306f\u7d30\u80de\u5185\u306e\u4e0d\u8981\u306a\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u5206\u89e3\u3059\u308b\u300c\u81ea\u98df\u4f5c\u7528\u300d\u3067\u3042\u308b\u300c<span style=\"color: #ff0000;\">\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc<\/span>\u300d\u306e\u4ed5\u7d44\u307f\u3092\u89e3\u660e\u3057\u305f\u304b\u3089\u3067\u3059\u3002<\/strong><\/span><\/p>\n<p><strong><span style=\"font-size: 20px;\">\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u306f1960\u5e74\u4ee3\u304b\u3089\u5927\u307e\u304b\u306a\u6982\u5ff5\u304c\u63d0\u5531\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u304c\u8a73\u7d30\u306f\u4e0d\u660e\u3067\u3057\u305f\u3002\u3000\u3000\u3000\u5927\u9685\u6c0f\u306f\u30011988\u5e74\u3054\u308d\u306b\u5358\u7d30\u80de\u751f\u7269\u306e\u9175\u6bcd\u3092\u89b3\u5bdf\u4e2d\u306b\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u3092\u4e16\u754c\u3067\u521d\u3081\u3066\u89b3\u5bdf\u3001\u305d\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u89e3\u660e\u3057\u307e\u3057\u305f\u3002<\/span><\/strong><\/p>\n<p><strong><span style=\"font-size: 20px;\">\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u306f<span style=\"background-color: #ffff99;\">\u4eba\u4f53\u5185\u306e\u30ea\u30b5\u30a4\u30af\u30eb\u6d3b\u52d5<\/span>\u306e\u3088\u3046\u306a\u3082\u306e\u3067<span style=\"text-decoration: underline;\">\u751f\u547d\u306b\u6b20\u304b\u305b\u306a\u3044\u6a5f\u80fd\u3068\u8a00\u3048\u307e\u3059\u3002<\/span>\u3053\u308c\u304c\u7570\u5e38\u3092\u8d77\u3053\u3059\u3068\u30ac\u30f3\u3084\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306a\u3069\u69d8\u3005\u306a\u75be\u60a3\u767a\u75c7\u3068\u95a2\u4fc2\u304c\u3042\u308b\u3068\u3055\u308c\u3001\u65b0\u305f\u306a\u5275\u85ac\u306b\u5f79\u7acb\u3064\u3068\u4e16\u754c\u4e2d\u304b\u3089\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/span><\/strong><\/p>\n<\/div>\n<\/div>\n<h2 style=\"text-align: center;\"><span class=\"ez-toc-section\" id=\"%E3%82%AA%E3%83%BC%E3%83%88%E3%83%95%E3%82%A1%E3%82%B8%E3%83%BC%E3%81%97%E3%82%88%E3%81%86-2\"><\/span><span style=\"font-size: 20px; background-color: #800080; color: #ffffff;\">\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u3057\u3088\u3046<\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<\/div>\n<div><center><img decoding=\"async\" src=\"https:\/\/www.aya199166.com\/wp-content\/uploads\/2023\/08\/osumi-216x300.png\" alt=\"\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u3057\u3088\u3046\" width=\"216\" height=\"300\" class=\"alignnone size-medium wp-image-508 aligncenter\" srcset=\"https:\/\/www.aya199166.com\/wp-content\/uploads\/2023\/08\/osumi-216x300.png 216w, https:\/\/www.aya199166.com\/wp-content\/uploads\/2023\/08\/osumi.png 281w\" sizes=\"(max-width: 216px) 100vw, 216px\" \/><\/center><\/div>\n<p><strong><span style=\"font-size: 20px; background-color: #ffffff;\">\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306f\u3001\u7d30\u80de\u5185\u30a8\u30cd\u30eb\u30ae\u30fc\u306e\u751f\u6210\u3092\u62c5\u3046\u91cd\u8981\u306a<a href=\"https:\/\/www.google.com\/search?q=%E3%82%AA%E3%83%AB%E3%82%AC%E3%83%8D%E3%83%A9&amp;oq=%E3%82%AA%E3%83%AB%E3%82%AC%E3%83%8D%E3%83%A9&amp;gs_lcrp=EgZjaHJvbWUyCQgAEEUYORiABDIHCAEQABiABDIHCAIQABiABDIHCAMQABiABDIHCAQQABiABDIHCAUQABiABDIHCAYQABiABDIHCAcQABiABDIHCAgQABiABDIHCAkQABiABNIBCTg4NjhqMGoxNagCALACAA&amp;sourceid=chrome&amp;ie=UTF-8\" style=\"background-color: #ffffff;\">\u30aa\u30eb\u30ac\u30cd\u30e9<\/a>\u3067\u3059\u3002<\/span><\/strong><br \/><strong><span style=\"font-size: 20px; background-color: #ffffff;\">\u3057\u304b\u3057\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306f\u8001\u5316\u3084\u640d\u50b7\u3092\u53d7\u3051\u308b\u3068\u3001\u7d30\u80de\u306b\u60aa\u5f71\u97ff\u3092\u53ca\u307c\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/span><\/strong><br \/><strong><span style=\"font-size: 20px; background-color: #ffffff;\">\u305d\u3053\u3067\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u3092\u5206\u89e3\u3059\u308b\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u304c\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/span><\/strong><\/p>\n<p><strong><span style=\"font-size: 20px; background-color: #ffffff;\">\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u306f\u3001\u7d30\u80de\u304c\u4e0d\u8981\u306a\u30bf\u30f3\u30d1\u30af\u8cea\u3084\u30aa\u30eb\u30ac\u30cd\u30e9\u3092\u5206\u89e3\u3059\u308b\u30d7\u30ed\u30bb\u30b9\u3067\u3059\u3002<\/span><\/strong><br \/><strong><span style=\"font-size: 20px; background-color: #ffffff;\">\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u306f\u3001\u7d30\u80de\u306e\u6052\u5e38\u6027\u3092\u7dad\u6301\u3057\u3001\u8001\u5316\u3084\u75be\u60a3\u306e\u4e88\u9632\u306b\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u307e\u3059\u3002<\/span><\/strong><\/p>\n<p><strong><span style=\"font-size: 20px; background-color: #ffffff;\">\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u3092\u5206\u89e3\u3059\u308b\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u3092<a href=\"https:\/\/ruo.mbl.co.jp\/bio\/product\/autophagy\/article\/mitophagy.html\" style=\"background-color: #ffffff;\">\u30de\u30a4\u30c8\u30d5\u30a1\u30b8\u30fc<\/a>\u3068\u547c\u3073\u307e\u3059\u3002<\/span><\/strong><br \/><strong><span style=\"font-size: 20px; background-color: #ffffff;\">\u30de\u30a4\u30c8\u30d5\u30a1\u30b8\u30fc\u306f\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u3092\u30aa\u30fc\u30c8\u30d5\u30a1\u30b4\u30bd\u30fc\u30e0\u3068\u547c\u3070\u308c\u308b\u5c0f\u80de\u306b\u5305\u307f\u8fbc\u307f\u3001\u5206\u89e3\u3057\u307e\u3059\u3002\u30de\u30a4\u30c8\u30d5\u30a1\u30b8\u30fc\u306f\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u8001\u5316\u3084\u640d\u50b7\u3092\u9632\u304e\u3001\u7d30\u80de\u306e\u5065\u5eb7\u3092\u7dad\u6301\u3059\u308b\u305f\u3081\u306b\u3001\u3068\u3066\u3082\u91cd\u8981\u3067\u3059\u3002<\/span><\/strong><\/p>\n<p><strong><span style=\"font-size: 20px; background-color: #ffffff;\">\u30de\u30a4\u30c8\u30d5\u30a1\u30b8\u30fc\u306e\u7814\u7a76\u306f\u3001\u8fd1\u5e74\u6025\u901f\u306b\u9032\u5c55\u3057\u3066\u6765\u3066\u3044\u307e\u3059\u3002<\/span><\/strong><br \/><strong><span style=\"font-size: 20px; background-color: #ffffff;\">2016\u5e74\u306b\u306f\u3001<a href=\"https:\/\/www.google.com\/search?q=Parkin%E3%81%A8PINK1&amp;oq=Parkin%E3%81%A8PINK1&amp;aqs=chrome..69i57j0i546l5.60074558j0j15&amp;sourceid=chrome&amp;ie=UTF-8\" style=\"background-color: #ffffff;\">Parkin\u3068PINK1<\/a>\u3068\u3044\u3046\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u3001\u30de\u30a4\u30c8\u30d5\u30a1\u30b8\u30fc\u306e\u8a98\u5c0e\u306b\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u89e3\u660e\u3055\u308c\u307e\u3057\u305f\u3002<\/span><\/strong><br \/><strong><span style=\"font-size: 20px; background-color: #ffffff;\">Parkin\u3068PINK1\u306f\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u640d\u50b7\u3092\u691c\u77e5\u3057\u3001\u30de\u30a4\u30c8\u30d5\u30a1\u30b8\u30fc\u3092\u8a98\u5c0e\u3057\u307e\u3059\u3002<\/span><\/strong><\/p>\n<p><strong><span style=\"font-size: 20px; background-color: #ffffff;\">\u30de\u30a4\u30c8\u30d5\u30a1\u30b8\u30fc\u306f\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u8001\u5316\u3084\u640d\u50b7\u3092\u9632\u3050\u3060\u3051\u3067\u306a\u304f\u3001\u7d30\u80de\u306e\u8001\u5316\u3084\u75be\u60a3\u306e\u4e88\u9632\u306b\u3082\u52b9\u679c\u7684\u3067\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/span><\/strong><br \/><strong><span style=\"font-size: 20px; background-color: #ffffff;\">\u4f8b\u3048\u3070\u3001\u30de\u30a6\u30b9\u306e\u809d\u81d3\u306bParkin\u3092\u904e\u5270\u767a\u73fe\u3055\u305b\u308b\u3068\u3001\u30df\u30c8\u30d5\u30a1\u30b8\u30fc\u304c\u6d3b\u6027\u5316\u3057\u3001\u809d\u81d3\u306e\u8001\u5316\u3084\u75be\u60a3\u304c\u6291\u5236\u3055\u308c\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/span><\/strong><\/p>\n<p><strong><span style=\"font-size: 20px; background-color: #ffffff;\">\u30de\u30a4\u30c8\u30d5\u30a1\u30b8\u30fc\u306f\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u5065\u5eb7\u3092\u7dad\u6301\u3057\u3001\u7d30\u80de\u306e\u8001\u5316\u3084\u75be\u60a3\u306e\u4e88\u9632\u306b\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u307e\u3059\u3002<\/span><\/strong><br \/><strong><span style=\"font-size: 20px; background-color: #ffffff;\">\u30de\u30a4\u30c8\u30d5\u30a1\u30b8\u30fc\u306e\u7814\u7a76\u306f\u3001\u4eca\u5f8c\u307e\u3059\u307e\u3059\u91cd\u8981\u6027\u3092\u5897\u3057\u3066\u3044\u304f\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/span><\/strong><\/p>\n<p><strong><span style=\"font-size: 20px; background-color: #ffffff;\">\u4ee5\u4e0b\u306b\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u3068\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u306b\u95a2\u3059\u308b\u7814\u7a76\u306e\u6210\u679c\u3092\u3044\u304f\u3064\u304b\u3054\u7d39\u4ecb\u3057\u307e\u3059\u3002<\/span><\/strong><\/p>\n<p><strong><span style=\"font-size: 20px; background-color: #ffffff;\">Parkin\u3068PINK1\u306f\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u640d\u50b7\u3092\u691c\u77e5\u3057\u3001\u30de\u30a4\u30c8\u30d5\u30a1\u30b8\u30fc\u3092\u8a98\u5c0e\u3057\u307e\u3059\u3002<\/span><\/strong><br \/><strong><span style=\"font-size: 20px; background-color: #ffffff;\">\u30de\u30a4\u30c8\u30d5\u30a1\u30b8\u30fc\u306f\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u8001\u5316\u3084\u640d\u50b7\u3092\u9632\u3050\u3060\u3051\u3067\u306a\u304f\u3001\u7d30\u80de\u306e\u8001\u5316\u3084\u75be\u60a3\u306e\u4e88\u9632\u306b\u3082\u52b9\u679c\u7684\u3067\u3059\u3002<\/span><\/strong><br \/><strong><span style=\"font-size: 20px; background-color: #ffffff;\">\u30de\u30a4\u30c8\u30d5\u30a1\u30b8\u30fc\u306f\u3001\u7d30\u80de\u306e\u6052\u5e38\u6027\u3092\u7dad\u6301\u3057\u3001\u7d30\u80de\u306e\u5065\u5eb7\u3092\u7dad\u6301\u3059\u308b\u305f\u3081\u306b\u91cd\u8981\u3067\u3059\u3002<\/span><\/strong><br \/><strong><span style=\"font-size: 20px; background-color: #ffffff;\">\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u3068\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u306b\u95a2\u3059\u308b\u7814\u7a76\u306f\u3001\u4eca\u5f8c\u307e\u3059\u307e\u3059\u91cd\u8981\u6027\u3092\u5897\u3057\u3066\u3044\u304f\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/span><\/strong><\/p>\n<p><strong><span style=\"font-size: 20px; background-color: #ffffff;\">\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u3068\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u306f\u3001\u7d30\u80de\u306e\u5065\u5eb7\u3092\u7dad\u6301\u3059\u308b\u305f\u3081\u306b\u91cd\u8981\u3067\u3059\u3002<\/span><\/strong><br \/><strong><span style=\"font-size: 20px; background-color: #ffffff;\">\u3057\u304b\u3057\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u640d\u50b7\u304c\u84c4\u7a4d\u3057\u305f\u308a\u3001\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u304c\u6a5f\u80fd\u4e0d\u5168\u306b\u9665\u3063\u305f\u308a\u3059\u308b\u3068\u3001\u7d30\u80de\u306e\u8001\u5316\u3084\u75be\u60a3\u3092\u5f15\u304d\u8d77\u3053\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/span><\/strong><\/p>\n<p><strong><span style=\"font-size: 20px; background-color: #ffffff;\">\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u640d\u50b7\u306f\u3001\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u3084\u708e\u75c7\u306a\u3069\u306b\u3088\u3063\u3066\u5f15\u304d\u8d77\u3053\u3055\u308c\u307e\u3059\u3002<\/span><\/strong><br \/><strong><span style=\"font-size: 20px; background-color: #ffffff;\">\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u3068\u306f\u3001\u6d3b\u6027\u9178\u7d20\u306e\u904e\u5270\u306a\u767a\u751f\u306b\u3088\u3063\u3066\u751f\u3058\u308b\u7d30\u80de\u306e\u30c0\u30e1\u30fc\u30b8\u3067\u3059\u3002\u708e\u75c7\u3068\u306f\u3001\u4f53\u5185\u306b\u4fb5\u5165\u3057\u305f\u75c5\u539f\u4f53\u3084\u7570\u7269\u306b\u5bfe\u3057\u3066\u3001\u4f53\u5185\u306e\u7d44\u7e54\u304c\u53cd\u5fdc\u3057\u3066\u8d77\u3053\u308b\u73fe\u8c61\u3067\u3059\u3002<\/span><\/strong><\/p>\n<p><strong><span style=\"font-size: 20px; background-color: #ffffff;\">\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u306f\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u640d\u50b7\u3092\u4fee\u5fa9\u3057\u305f\u308a\u3001\u4e0d\u8981\u306a\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u3092\u9664\u53bb\u3057\u305f\u308a\u3059\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u5065\u5eb7\u3092\u7dad\u6301\u3057\u3066\u3044\u307e\u3059\u3002<\/span><\/strong><br \/><strong><span style=\"font-size: 20px; background-color: #ffffff;\">\u3057\u304b\u3057\u3001\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u304c\u6a5f\u80fd\u4e0d\u5168\u306b\u9665\u308b\u3068\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u640d\u50b7\u304c\u84c4\u7a4d\u3057\u3001\u7d30\u80de\u306e\u8001\u5316\u3084\u75be\u60a3\u3092\u5f15\u304d\u8d77\u3053\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/span><\/strong><\/p>\n<p><strong><span style=\"font-size: 20px; background-color: #ffffff;\">\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u640d\u50b7\u3084\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u306e\u6a5f\u80fd\u4e0d\u5168\u3092\u9632\u3050\u305f\u3081\u306b\u306f\u3001\u5065\u5eb7\u7684\u306a\u98df\u751f\u6d3b\u3084\u904b\u52d5\u3092\u5fc3\u304c\u3051\u308b\u3053\u3068\u304c\u5927\u5207\u3067\u3059\u3002<\/span><\/strong><br \/><strong><span style=\"font-size: 20px; background-color: #ffffff;\">\u5065\u5eb7\u7684\u306a\u98df\u751f\u6d3b\u3068\u306f\u3001\u91ce\u83dc\u3084\u679c\u7269\u3001\u5168\u7c92\u7a40\u7269\u3001\u9b5a\u4ecb\u985e\u3092\u591a\u304f\u6442\u53d6\u3059\u308b\u98df\u751f\u6d3b\u3067\u3059\u3002<\/span><\/strong><br \/><strong><span style=\"font-size: 20px; background-color: #ffffff;\">\u904b\u52d5\u3068\u306f\u3001\u9031\u306b150\u5206\u4ee5\u4e0a\u306e\u4e2d\u7a0b\u5ea6\u306e\u5f37\u5ea6\u306e\u904b\u52d5\u3092\u7d99\u7d9a\u7684\u306b\u884c\u3046\u3053\u3068\u3067\u3059\u3002<\/span><\/strong><\/p>\n<p><strong><span style=\"font-size: 20px; background-color: #ffffff;\">\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u640d\u50b7\u3084\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u306e\u6a5f\u80fd\u4e0d\u5168\u304c\u7591\u308f\u308c\u308b\u5834\u5408\u306b\u306f\u3001\u533b\u5e2b\u306e\u8a3a\u5bdf\u3092\u53d7\u3051\u308b\u3053\u3068\u3092\u304a\u52e7\u3081\u3057\u307e\u3059\u3002\u307e\u305f\u3001\u79c1\u306enote\u30d6\u30ed\u30b0\u8a18\u4e8b\u306b<a href=\"https:\/\/note.com\/rich_quince717\/n\/n67da7493aef5\" style=\"background-color: #ffffff;\">\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u3068\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc<\/a>\u3068\u3044\u3046\u30bf\u30a4\u30c8\u30eb\u304c\u3042\u308a\u307e\u3059\u3002\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u5185\u5bb9\u306f\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u306f\u304a\u6c17\u697d\u306a\u30c0\u30a4\u30a8\u30c3\u30c8\u65b9\u6cd5\u306a\u3093\u304b\u3067\u306f\u306a\u3044\u7684\u306a\u3082\u306e\u3067\u3059\u3002<\/span><\/strong><\/p>\n<center><img decoding=\"async\" src=\"https:\/\/www.aya199166.com\/wp-content\/uploads\/2023\/08\/66c19942ab4ba346fdb64ccc04cde373-300x300.jpg\" alt=\"\u30aa\u30fc\u30c8 \u30d5\u30a1\u30b8\u30fc \u3057\u3088\u3046\" width=\"300\" height=\"300\" class=\"alignnone size-medium wp-image-517 aligncenter\" srcset=\"https:\/\/www.aya199166.com\/wp-content\/uploads\/2023\/08\/66c19942ab4ba346fdb64ccc04cde373-300x300.jpg 300w, https:\/\/www.aya199166.com\/wp-content\/uploads\/2023\/08\/66c19942ab4ba346fdb64ccc04cde373-150x150.jpg 150w, https:\/\/www.aya199166.com\/wp-content\/uploads\/2023\/08\/66c19942ab4ba346fdb64ccc04cde373.jpg 825w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/center>\n<h3 style=\"text-align: center;\"><span class=\"ez-toc-section\" id=\"%E3%82%AA%E3%83%BC%E3%83%88%E3%83%95%E3%82%A1%E3%82%B8%E3%83%BC%E3%81%97%E3%82%88%E3%81%86-3\"><\/span>\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u3057\u3088\u3046<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p style=\"text-align: center;\"><span style=\"text-decoration: underline; font-size: 20px;\"><span style=\"color: #000000; text-decoration: underline;\"><strong>\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u306f\u3001\u7d30\u80de\u306e\u6052\u5e38\u6027\u3092\u7dad\u6301\u3057\u3001\u8001\u5316\u3084\u75be\u60a3\u306e\u4e88\u9632<\/strong><\/span><\/span><\/p>\n<p style=\"text-align: center;\"><span style=\"text-decoration: underline; font-size: 20px;\"><span style=\"color: #000000; text-decoration: underline;\"><strong>\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u307e\u3059\u3002<\/strong><\/span><\/span><\/p>\n<p><span style=\"font-size: 20px;\"><strong><span style=\"background-color: #ffcc99;\">\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u306e\u904e\u7a0b\u306f\u3001\u6b21\u306e\u3068\u304a\u308a\u3067\u3059\u3002<\/span><\/strong><\/span><\/p>\n<p><span style=\"font-size: 20px;\"><strong>\u7d30\u80de\u306f\u4e0d\u8981\u306a\u30bf\u30f3\u30d1\u30af\u8cea\u3084\u30aa\u30eb\u30ac\u30cd\u30e9\u3092\u5305\u307f\u8fbc\u3080\u5c0f\u80de\u3092\u5f62\u6210\u3057\u307e\u3059\u3002<\/strong><\/span><br \/><span style=\"font-size: 20px;\"><strong>\u5c0f\u80de\u306f\u3001\u30aa\u30fc\u30c8\u30d5\u30a1\u30b4\u30bd\u30fc\u30e0\u3068\u547c\u3070\u308c\u308b\u5c0f\u80de\u306b\u878d\u5408\u3057\u307e\u3059\u3002<\/strong><\/span><br \/><span style=\"font-size: 20px;\"><strong>\u30aa\u30fc\u30c8\u30d5\u30a1\u30b4\u30bd\u30fc\u30e0\u306f\u3001\u30ea\u30bd\u30bd\u30fc\u30e0\u3068\u878d\u5408\u3057\u307e\u3059\u3002<\/strong><\/span><br \/><span style=\"font-size: 20px;\"><strong>\u30ea\u30bd\u30bd\u30fc\u30e0\u306f\u3001\u30aa\u30fc\u30c8\u30d5\u30a1\u30b4\u30bd\u30fc\u30e0\u5185\u306e\u4e0d\u8981\u306a\u30bf\u30f3\u30d1\u30af\u8cea\u3084\u30aa\u30eb\u30ac\u30cd\u30e9\u3092\u5206\u89e3\u3057\u307e\u3059\u3002<\/strong><\/span><br \/><span style=\"font-size: 20px;\"><strong>\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u306f\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u8001\u5316\u3084\u640d\u50b7\u3092\u9632\u3050\u305f\u3081\u306b\u91cd\u8981\u3067\u3059\u3002\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u306f\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u3092\u5206\u89e3\u3059\u308b\u3053\u3068\u3067\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u8001\u5316\u3084\u640d\u50b7\u3092\u9632\u304e\u3001\u7d30\u80de\u306e\u5065\u5eb7\u3092\u7dad\u6301\u3057\u3066\u3044\u307e\u3059\u3002<\/strong><\/span><\/p>\n<p><span style=\"font-size: 20px;\"><strong>\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u306f\u3001\u7d30\u80de\u306e\u8001\u5316\u3084\u75be\u60a3\u306e\u4e88\u9632\u306b\u3082\u52b9\u679c\u7684\u3067\u3059\u3002<\/strong><\/span><br \/><span style=\"font-size: 20px;\"><strong>\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u306f\u3001\u7d30\u80de\u306e\u8001\u5316\u3084\u75be\u60a3\u3092\u5f15\u304d\u8d77\u3053\u3059\u30bf\u30f3\u30d1\u30af\u8cea\u3084\u30aa\u30eb\u30ac\u30cd\u30e9\u3092\u5206\u89e3\u3059\u308b\u3053\u3068\u3067\u3001\u7d30\u80de\u306e\u8001\u5316\u3084\u75be\u60a3\u3092\u4e88\u9632\u3057\u3066\u3044\u307e\u3059\u3002<\/strong><\/span><\/p>\n<p><span style=\"font-size: 20px; 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